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提醒:Nature Reviews Neuroscience - Issue - nature.com science feeds
【标题】Neurodegenerative disease: Preventing 'SIRTain' death by mutant huntingtin
【摘要】neurodegenerative disease: preventing 'sirtain' death by mutant huntingtinnature reviews neuroscience 13, 71 (2012). doi:10.1038/nrn3182author: monica hoyos flighttwo independent studies link mutant huntingtin to inactivation of the deacetylase enzyme sirt1 and highlight a neuroprotective role for sirt1 in mouse models of huntington's disease.... (01-21 04:11)