哪吒机器人提醒：
提醒：Genome Biology - Latest Articles
【标题】Predicting the effects of frameshifting indels
【摘要】each human has approximately 50-280 frameshifting indels, yet their implications are unknown. we created sift indel, a prediction method for frameshifting indels which has 84% accuracy. the percentage of human frameshifting indels predicted to be gene-damaging is negatively correlated with allele frequency. we also show that although the first frameshifting indel in a gene causes loss of function, there is a tendency for the second frameshifting indel to compensate and restore protein function. ... (02-10 00:08)
手机哪吒网 m.iNezha.com 有人网